Yes you can have one key that works at both locations, home and office.
Many of our customers, normally in management positions at their place of work, use their work master key for their home. In these situations, we typically make a separate key for the house that the rest of the family can use so that the business is not at risk. This makes it easier for our client to access the business or commercial lock and the home lock with one key. Depending on the situation, we may have to upgrade the deadbolts or locks on the home so that they work with the office master key. Sometimes we do have to up-grade the homes locks but this is also for the good.